The directive came after Australian pharmacies saw a rush of people presenting scripts for the drugs hydroxychloroquine — sold as Plaquenil — and chloroquine from their GPs, or asking to buy it over the counter. Demand skyrocketed following a press conference by US President Donald Trump last week, in which he touted the drugs as a "game-changer" — comments based on a World Health Organisation report labelling the drugs a "potentially useful" preventative and curative treatment for COVID Pharmaceutical Society of Australia president Chris Freeman said Australian pharmacies had seen unprecedented demand for the medications, creating a shortage for patients who actually needed them.
He said while there were "positive signals" from the drugs in the fight against coronavirus he called on people not to "buy into the hype". Both drugs are used to treat rheumatoid arthritis — a disease where patients can spend years trialling drugs until they find one that is right for them. If too much pressure is put on supplies, potential shortages will mean patients who miss out on their regular drugs may experience painful flare-ups, experts say.
AMA committee member Chris Moy told the ABC the drugs were not widely used in Australia and warned regulation may be needed to limit their supply to the patients who actually needed them. In laboratory tests chloroquine has been found to be effective against some viruses such as chikungunya, dengue, and influenza.
But the WHO report, released earlier this month, said in studies with animals and in randomised controlled trials with humans the medication had been largely disappointing against COVID Medical experts say the advantage of chloroquine — approved for inflammatory conditions and the suppression and treatment of malaria — is that it is relatively safe, has few side effects and is cheap to produce. David Paterson, from the University of Queensland, said chloroquine, along with an older HIV medication, had been found to kill coronavirus in laboratory tests. His team at the Centre for Clinical Research hopes to start human trials in as little as three months.
Scientists are also investigating whether hydroxychloroquine and chloroquine might be useful as a preventative treatment. Up to 20, international healthcare workers will be recruited and given a small daily dose of chloroquine for three months. Dr Freeman said the rush for hydroxychloroquine and chloroquine, and the number of prescriptions in the system, were part of a disturbing trend. We're even seeing dentists prescribing to the community outside the context of dental work.
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